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Top 5 Largest Healthcare Companies in USA 2022

There are numerous healthcare companies in the United States across various sectors, including pharmaceuticals, biotechnology, medical devices, healthcare services, and health insurance. Here are some prominent healthcare companies in the U.S

1. CVS Healthcare

CVS Health Corporation is a prominent healthcare company in the United States. Here are some key details about CVS Health:


CVS Health is a diversified healthcare company that operates in multiple segments, including retail pharmacy, pharmacy benefit management (PBM), and healthcare services.

Retail Pharmacy:

CVS operates one of the largest pharmacy chains in the U.S., with over 9,900 retail locations. These stores offer prescription medications, over-the-counter drugs, health and wellness products, and various other healthcare services.

Pharmacy Benefit Management (PBM):

CVS Health owns and operates CVS Caremark, a leading pharmacy benefit management company. It works with employers, health insurance providers, and government programs to administer prescription drug plans, manage costs, and provide convenient access to medications for individuals.

2. McKesson healthcare

McKesson Corporation is a major healthcare company in the United States. Here is an overview of McKesson:


McKesson Corporation is one of the largest healthcare services and information technology companies globally.

Pharmaceutical Distribution:

McKesson is a leading distributor of pharmaceuticals and medical supplies. It works with pharmaceutical manufacturers, pharmacies, hospitals, clinics, and other healthcare providers to ensure the efficient and secure distribution of medications and healthcare products.

Healthcare Technology Solutions:

McKesson provides a range of technology solutions to improve healthcare delivery and management. This includes electronic health record (EHR) systems, clinical decision support systems, revenue cycle management solutions, and supply chain management tools.

3. UnitedHealth Group


UnitedHealthcare is a division of UnitedHealth Group, a diversified healthcare company. It offers a wide range of health insurance products and related services to individuals, employers, and government programs.

Health Insurance Plans:

UnitedHealthcare provides various health insurance plans, including individual and family plans, employer-sponsored group plans, Medicare Advantage plans, Medicaid plans, and other government programs. These plans offer coverage for medical services, prescription drugs, preventive care, and other healthcare needs.

Network of Providers:

UnitedHealthcare has an extensive network of healthcare providers, including doctors, hospitals, clinics, specialists, and pharmacies. The network allows members to access healthcare services from participating providers at negotiated rates.

4. Johnson and Johnson

Johnson & Johnson is a multinational healthcare company based in the United States. Here is an overview of Johnson & Johnson:


Johnson & Johnson (J&J) is one of the largest and most diversified healthcare companies globally. It operates in three primary segments: pharmaceuticals, medical devices, and consumer health.


J&J’s pharmaceutical division focuses on developing and manufacturing prescription drugs across various therapeutic areas. It produces medications for conditions like cardiovascular diseases, oncology, immunology, infectious diseases, neuroscience, and more.

Medical Devices:

J&J’s medical devices segment designs, manufactures, and markets a broad range of medical devices and equipment. This includes surgical instruments, orthopedic implants, vision care products, diabetes care products, and minimally invasive surgical solutions.

5. Express Scripts Holdings

Express Scripts Holdings is a prominent healthcare company in the United States that primarily operates as a pharmacy benefit management (PBM) organization. Here is an overview of Express Scripts Holdings:


Express Scripts Holdings, commonly known as Express Scripts, is a subsidiary of Cigna Corporation since its acquisition in 2018. It is one of the largest pharmacy benefit management companies in the United States.

Pharmacy Benefit Management (PBM):

Express Scripts works with employers, health insurance providers, government programs, and other organizations to administer prescription drug programs. As a PBM, it manages prescription drug benefits, negotiates pricing with pharmacies and pharmaceutical manufacturers, processes claims, and provides clinical and formulary management services.

Prescription Fulfillment and Mail Order Pharmacy:

Express Scripts operates its own mail order pharmacy, allowing members to conveniently obtain maintenance medications through home delivery. This service helps improve medication adherence and offers cost-saving opportunities for patients.

Express Scripts Holdings plays a crucial role in managing prescription drug benefits and optimizing medication therapy for individuals and organizations in the United States. It aims to improve medication access, affordability, and patient outcomes through its comprehensive PBM services and innovative solutions.