Erythromycin stearate is one of the most commonly used antibiotics in treating bacterial infections, both respiratory and skin. It is in the macrolide category of antibiotics, and it functions by hindering the protein synthesis of dangerous bacteria, therefore halting their development.
Available for both adult and child uses, erythromycin stearate is very efficient in combating infections such as pneumonia, bronchitis, and special transmitted diseases.
Still, although it is considered one of the most efficient treatments, all medications are known to have side effects and precautions that must be learned.
Mild gastrointestinal disturbances are the least serious manifestation of erythromycin stearate. They can present themselves clinically as nausea and diarrhea, whereas severe manifestations of the medicine include toxic hepatitis and an arrhythmia.
The side effects then should be closely monitored and anyone who has taken this antibiotic should know what signs to look out for and how to cope with them to balance the benefits of taking this particular antibiotic.
However, there are some side effects also. Therefore patients with certain diseases or those taking another medicine should exercise a lot of caution.
In this article, we are going to analyze the Erythromycin stearate manufacturer details of erythromycin stearate, its side effects including their frequency and possible occurrence of some uncommon side effects, and special precautions to be taken during its usage. As a patient or a healthcare provider, this information will assist you in coming up with the right decisions regarding its use.
Uses of Erythromycin Stearate
Erythromycin stearate is mainly prescribed for the cure of numerous bacterial infections. Its action as a macrolide antibiotic is based upon the prevention of bacterial protein synthesis hence discouraging the growth of hazardous bacteria. It is usually used for treating bacterial pneumonia, bronchitis, whooping cough, pimples, and cellulitis.
It also has applications in the cure of ear infections, Chlamydia – it is a transmitted disease, and throat infections that include Streptococcal pharyngitis. Also, erythromycin stearate can be administered for the prevention or treatment of bacterial infections in patients with an allergy to penicillin and its analogs, including amoxicillin.
Erythromycin is sometimes employed because of its anti-inflammatory properties with rosacea as one of the conditions that are treated using the medicine. In off-label use, it can also be used as a prokinetic where the stomach is unable to empty itself expeditiously as is the case with gastroparesis.
However, like all antibiotics, it should be taken under the doctor’s prescription to be sure it will work effectively and will not contribute to the emergence of antibiotic-resistant bacteria.
Common Side Effects of Erythromycin Stearate
Erythromycin stearate is an antibiotic for treating bacteria-caused infections, but it has several side effects that erupt in instances of mild to severe symptoms. These side effects are usually dose-related and may occur in any system of the body or organ.
Gastrointestinal problems are part of the most frequently reported side effects of LOR. These include nausea-vomiting, stomach pains, stomach rumbling, and loose motions. That is why, high doses or, prolonged use might result in the development of such problems, as erythromycin is known to change the bacterial flora in the gastrointestinal tract. Reduced appetite – this side effect may manifest in some patients taking Robinson et al.’s (2005) medicine with reduced thirst, anorexia, or loss of appetite in general. Some of these side effects may be relieved by taking the medication with food.
Hepatic effects surprised me as well. Kupchan and his associates discovered that erythromycin is metabolized in the liver, and it may lead to jaundice or hepatitis in some patients particularly those with liver ailments. The manifestations of liver toxicity include; general body weakness, fatigue, and high levels of enzymes in the blood associated with liver complications.
Cardiovascular complications include prolongation of the QT interval, a potentially fatal heart rhythm problem known as Torsades de pointes, especially in patients with heart problems. Hypotension (low blood pressure) is also possible and its symptoms include dizziness or fainting.
Reactions and Side Effects
Reactions and side effects Some people develop skin rashes or in rare circumstances, an anaphylactic reaction is possible, which mandates a visit to the physician. Also, hearing impairment or ototoxicity may develop; some patients may develop reversible hearing loss after high doses or long-term therapy.
Last but not least; similar to any antibiotic agents, the balance of the local microbial flora often gets upset and the superinfections- susceptibility to fungal or antibiotic-resistant organisms arise.
Contraindications
Macrolides hypersensitivity reaction
Unter this there are different reactions that a patient may develop due to macrolide an example of which is;
The following should never be used with erythromycin stearate therapy if he or she is diagnosed with it. These sensitivities may develop to any grade starting with a breakout on the skin to the severe type of anaphylaxis.
Liver Disease
It is hepatically metabolized and should not be given to any patient with liver diseases, such as cirrhosis or hepatitis. It may also necessitate baseline and during-treatment liver function tests, and it may be necessary to alternate dosages or change antibiotics.
medicine Interactions
Erythromycin can also interact with several other medicines. Some of the most important interactions include:
- Statins
- Warfarin
- Anticonvulsants
A list of possible interactions that are to be had before therapy must be checked, especially when the patient is on more than one medicine.
Renal Function
A renal impairment may also affect the clearance of erythromycin particularly if given in high concentrations for the long term. Special precautions regarding dose may be given to the patient especially when the patient has severe renal impairment.
Conclusion
It is an erythromycin derivative stearate and like other macrolide antibiotics, this antibiotic is used to treat a variety of conditions including respiratory, skin, and gastrointestinal infections. It is a quite often used safe and well-tolerated medicine nevertheless it has side effects that are typical for macrolide antibiotics – pro- and Possibly severe gastroenteritis, liver dysfunction, and allergic reactions.
Patients should discuss their medical history with the physician, the medications they are taking, and, or any previous allergic reactions they’ve had with macrolide antibiotics. There are necessary precautions in monitoring patients to ensure that side effects are reduced to the barest extent for example, in patients with liver or kidney ailments, or on other medicines that have interaction with erythromycin.